What is the antidote for heparin administration during hemodialysis?

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The correct antidote for heparin administration during hemodialysis is protamine sulfate. Heparin is an anticoagulant commonly used during dialysis to prevent clotting in the dialysis machine and the patient's bloodstream. In situations where there is a need to reverse the effects of heparin, such as in cases of bleeding or surgical intervention, protamine sulfate is utilized due to its capability to bind to heparin, effectively neutralizing its anticoagulant effects.

Protamine sulfate works by forming a stable complex with heparin that inhibits its action, thereby reversing its anticoagulation properties. This is particularly important in patients undergoing hemodialysis, as optimal anticoagulation management is crucial for the safety and effectiveness of the procedure.

Other options like vitamin K are used for reversing the effects of vitamin K antagonists, specifically warfarin, and are not effective against heparin. Amiodarone is an antiarrhythmic medication not related to heparin reversal. Calcium chloride (CaCl2) is utilized for different medical indications, such as in the treatment of hypocalcemia or during cardiopulmonary resuscitation, but does not reverse the effects of heparin.

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