What condition is characterized by significant involuntary urination during sleep?

The condition characterized by significant involuntary urination during sleep is enuresis. This term specifically refers to the involuntary discharge of urine, typically occurring in children during the night. Enuresis can manifest as primary, where the child has never been dry at night, or secondary, where the child who was previously dry starts wetting the bed again, often due to stress or medical conditions.

Diabetes, while it can lead to frequent urination due to high blood sugar levels, does not specifically refer to involuntary urination during sleep. Similarly, incontinence is a broader term that encompasses various types of involuntary urination at any time, not just during sleep. Nocturia refers to the need to wake up during the night to urinate and is more associated with frequent urination rather than involuntary urination while asleep. Thus, enuresis is the precise term that identifies this specific condition.